171 Ashley Ave.
Charleston, SC 29425
843-792-1414
800-424-MUSC
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February 2005
This edition:
Letter from the Chair
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L. Lyndon Key, MD
Professor and Chairman
Department of Pediatrics |
Dear Children's Research Institute staff and supporters:
We are grateful for the fantastic effort that has brought the Charles P. Darby Children's Research Institute
into being. Special thanks goes out to the work of the University and
its officials, the Darby Family, the more than 2000 contributors to the building, and the many members of the
University family who have helped in planning,
creating, and implementing the programs which will provide such wonderful opportunities to further the
health of children.
We have honored Dr. Charles Darby in several issues of our newsletter for the major role that he and his
family have played as the creators and founders
of the program. We must remember, however, the great contribution of the University, spearheaded by Dr. Ray
Greenberg, Dr. John Raymond, and Dr. Jerry Reves.
With a strong base and the ability to create new and exciting centers of excellence within the CRI, we will
succeed in bettering the lives of children and adults.
This week marks the beginning of the Institute's life. We, as pediatricians, know the importance of a good
start and a nurturing beginning. Last week we
heard Dr. David Nathan proclaim that the beginning of any new program starts with the basics. This includes
basic understandings of cellular and
physiological processes. He also told us that basic discovery means little if we are unable to
translate these discoveries into clinical
advances. This bed-to-bench-to-bed-model is what we are striving to achieve.
On February 17, we will be providing a symposium that will feature the scientists working in
the CRI. Researchers within the Institute
will learn what their fellow investigators are studying in their labs and will walk away with their heads
swimming with new ideas to apply to their own
research. Clinicians will hear about basic physiology and will be inspired to think how novel concepts can
be applied to the care of their patients.
Administrators will be exposed to the workings of the Institute and will learn first hand what areas of
strength can help to drive the University's
research portfolio to new heights.
I would like to thank Drs. Bernie Maria and Inderjit Singh for their work in creating this symposium. This
is indeed a moment of pride, and a time to
thank the many contributors to the creation of the Institute. I would like to thank those who were helped to
understand the importance of this project
by our Children's Hospital Fund led by Barbara Rivers and her fabulous staff, supported and directed by
superb boards (chaired during the campaign by
Linda Woodside, John Thompson, and Tom McNally). We thank the University administration and development for
their role in supporting this project.
I must thank Leslie Kendall for her role in overseeing the construction, completion and operation of the
building. I wish to thank Sabra Slaughter and
Jim Fisher and the CRI Grand Opening Committee for their help in planning for the opening and working with
us on the development of our funding base.
Finally, I would like to thank my wife Janice and Mrs. Joyce Darby for their many hours of work and their
sleepless nights worrying about important
details that I would have forgotten
Last but not least, I would like to thank the faculty for their tremendous response to my plea to help us with getting
the building named after Charlie. We raised
more than $250,000 before the campaign was completed. Thank you for your generosity. Now, I want to exhort each
of you to be present for as many of the
seminars as possible. The success of the programs will depend on how well they are integrated into the
fabric of the Children's Hospital culture.
Sincerely,
L. Lyndon Key, MD
Chair, Department of Pediatrics
Update from the Administrator
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John Sanders, MHA
Administrator
MUSC Children's Hospital |
Children's Hospital to Open Medically Fragile Children's Program
The MUSC Children's Hospital is set to open the Medically Fragile Children's Program during the spring.
This service will replicate a very successful program located in Columbia. Working with Health and Human
Services and the Department of Social Services, a model of care has been created to provide coordinated
and complete care for medically fragile children. By providing a location where these medically complex
children can go for total care has created outstanding results in the Palmetto program. Children receive
the care when they need it and they are able to reach their potentials quicker, utilize emergency rooms
and inpatient stays less and for foster children, the rate of adoption has increased dramatically.
We plan to open our MFCP at the old Baker/Roper Hospital located at the junction of Cosgrove and I-26.
Over the next few weeks the space will be renovated and staff will be hired as we look forward to an
opening by May. The children that will initially be accepted into the program will be in foster care.
Over time we will move to open the program to other medically fragile children. This is an exciting
program that we are anxious to open to better care for this very important population.
Children's Research Institute News Brief
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Bernard L. Maria, MD, MBA
Executive Director
Children's Research Institute |
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Inderjit Singh, PhD
Scientific Director
Children's Research Institute |
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The Charles P. Darby Children's Research Institute's mission to improve the lives of children and their families and communities by conducting high-quality pediatric research, training superior physicians and scientists, and fostering innovation through the sciences of discovery and application. Our vision is to be a leading regional, national and international resource in children's research. Our goals, in support of the mission and vision, are to:
- Empower talented MUSC scientists, physician researchers, and practitioners to improve child and adolescent health;
- Promote inclusiveness and collaboration;
- Identify and enable established investigators;
- Identify and enable young or new investigators;
- Increase and diversify funding for research; and
- Optimize use of research space.
These goals will enable multidisciplinary and collaborative groups of scientists to employ innovative research strategies.
Importantly, the Children's Research Institute will allow MUSC to attract and retain a critical mass of talented investigators.
One week following the dedication and opening of the Institute, we will convene for a mini-symposium on February 17 to
hear from each of our research programs. The forum promises to be an outstanding opportunity for pediatric faculty and
other physicians to hear about current research and potential benchtop to bedside collaborations. While there has been
a good deal of discussion over the years on what to expect from the Institute and its programs, it is a wonderful feeling
to now move to a phase where returns on the investment are realized for children. Please join us for an intellectual tour
of the Institute!
Agenda and Format
CRI Investigators Forum Mini-Symposium
BSB 502
February 17, 2005
8 - 1 p.m.
CRI Investigators Forum and Data Blitz
8 a.m. - 8:05 a.m.
Introduction and Statement of Goals
2nd Floor Activities
8:05 a.m. - 8:20 a.m.
Pediatric Obesity, Insulin Resistance, and Diabetes
Program Director: Richard Furlanetto, MD, PhD
8:20 a.m. - 8:35 a.m.
Childhood Autoimmune Rheumatic Diseases
Program Directors: Richard Silver, MD, Stephen Tomlinson, PhD, and
Gary Gilkeson, MD
8:35 a.m. - 8:50 a.m.
Osteoclast Biology and Bone Disease
Program Director: Sakamuri Reddy, PhD
3rd Floor Activities
8:50 a.m. - 9:10 a.m.
Antenatal and Early Childhood Nutrition
Program Directors: Bruce W. Hollis, Ph.D and Carol Wagner, MD
9:10 a.m. - 9:30 a.m.
Pediatric Pulmonary Biology
Program Director: John E. Baatz, PhD
9:30 a.m. - 9:50 a.m.
Proteomics Center and Bioengineering
Program Director: Daniel Knaap, PhD
9:50 a.m. - 10:10 a.m.
BREAK
4th Floor Activities
10:10 a.m. - 10:30 a.m.
Pediatric Neuropsychiatry
Program Director: Peter Kalivas, PhD
10:30 a.m. - 10:50 a.m.
Childhood Cancer and Blood Disorders
Program Director: Julio Barredo, MD
10:50 a.m. - 11:10 a.m.
Drug Disposition and Pharmacogenetics
Program Director: C. Lindsay DeVane, PharmD
5th Floor Activities
11:10 a.m. - 11:30 a.m.
Developmental Neurological Disorders & Lipidomics
Program Director: Inderjit Singh, PhD
6th Floor Activities
11:30 a.m. - 11:50 a.m.
Pediatric Cardiogenomic Biology & Cardiovascular Developmental Biology
Program Directors: Roger Markwald, PhD and J. Philip Saul
11:50 a.m. - 12:00 p.m.
Closing Comments
12:00 p.m. - 1:00 p.m.
LUNCH
Mental Health Resource News Brief
Improving Self-Esteem in Children
Self-esteem is instrumental in helping children avoid behaviors that risk health and safety and primary care health
providers can help parents teach their children that failure and mistakes are an inevitable, but ultimately useful,
part of life. For more tips please see Bright Futures in Practice: Mental Health Practice Guide and Tool Kit.
Please join our breakfast study group on the third Tuesday of each month in room 377 Rutledge Tower at 8 a.m. for
review of strategies for addressing mental health issues in medical settings. Contact
spratte@musc.edu for additional information.
A special thanks to the following individuals for their efforts in putting together Kids Connection each month.
Managing Editor: Bernard L. Maria, MD, MBA
Assistant Editor: Mary Jacobs
Publisher: Jessica Munday (Trio Solutions Inc.)
Web design: Jennifer Cherock (Trio Solutions Inc.) and Brian Dadin (MUSC IT Lab)
Contributing Writers: Lyndon Key, MD; Bernard Maria, MD; and John Sanders
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